A natural solution to support animal health and performance whilst safeguarding antibiotics, protecting against antimicrobial resistance.
Orego-Stim Forte is developed from a unique source of 100% natural oregano essential oil (OEO) and contains multiple compounds which work in synergy to offer several well documented properties and functions.
Key Benefits
- Helps reduce reliance on antibiotics.
- Includes flavouring compounds that can help to enhance the appetite and feed intakes even during stress periods.
- Contains anti-oxidants which support a healthy immune system and help to maintain fast growing species.
- Oregano essential oil can help maintain normal gut function and digestion.
- Quality Guaranteed
The Story of a Single Drop
This is the story of a single drop. Anpario takes great pride in the decades of research, manufacturing precision and strict quality processes that lead to the superior performance of the Orego-Stim product range. Sustainably delivering value, performance and higher profitability for producers worldwide.
From Process to Product
The natural Oregano Essential Oil (OEO) in Orego-Stim is extracted from Anpario’s exclusive oregano strain, cultivated organically in central Europe. From point of harvest through the unique extraction method and onward production processes, we protect the active properties in the natural oil to ensure a high-quality product every time.
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Regular testing
Anpario take quality very seriously and testing starts before plants are harvested. Samples are taken from the crop to determine the levels of the main active ingredients, carvacrol, ρ-cymene and thymol, and at exactly the right time, the plants are harvested and brought to the distillery for oil extraction by steam distillation.
Anpario’s procedures of regular and routine testing of our oregano oil is essential and ensures that the Orego-Stim you buy is the same every time, avoiding undesirable variability.
Processing and manufacture
Significant research and expertise underpins the manufacture of the Orego-Stim product range, available in powder or liquid form.
Specially selected mineral carriers ensure a free-flowing and homogenous finished powder product. This is vital to any manufacturing process to allow even dispersion in the final feed. Orego-Stim Powder is then packed into foil bags and sealed to maintain the freshness over the two year shelf life. The selection of emulsifier and unique manufacturing process ensures our liquid formulation disperses easily and thoroughly in water for easy application.
Orego-Stim is unique as only the natural whole oil is used.
Orego-stim contains naturally occurring compounds which work in synergy to offer several well-documented properties and functions of OEO.
Natural Whole Oil
100%
Components
100+
Synthetic Compounds
0%
Consistency in every batch
Oregano Essential Oil used to produce Orego-Stim consists of 100+ naturally occurring active compounds, frequent monitoring ensures consistent quality batch after batch, which is vital to ensure product performance.
- Vibriosis
Vibriosis in Shrimp Aquaculture
Vibriosis is one of the most significant bacterial diseases affecting shrimp aquaculture worldwide, caused by pathogenic bacteria from the Vibrio genus such as V. parahaemolyticus, V. harveyi, V. alginolyticus, V. campbellii. These opportunistic pathogens are ubiquitous in marine and brackish environments and thrive in aquaculture systems, particularly under poor water quality, warmer temperatures, and stressful farming conditions (Harpeni et al., 2024; Chandrakala and Priya, 2017). Vibriosis is especially notorious for its association with some of the major bacterial diseases in shrimp aquaculture:
Acute Hepatopancreatic Necrosis Disease (AHPND), formerly known as Early Mortality Syndrome (EMS), is caused by specific strains of V. parahaemolyticus that carry the PirA and PirB toxin genes, which lead to necrosis of the hepatopancreas, a crucial organ for digestion and immunity in shrimp (Yang et al., 2022; Amalia et al., 2024).
White Faeces Syndrome (WFS) is a multifactorial disease associated with infections caused by Enterocytozoon hepatopenaei (EHP), a microsporidian parasite, and Vibrio spp., particularly V. parahaemolyticus (Elias et al., 2023). EHP infects the hepatopancreas, disrupting nutrient digestion and absorption, leading to poor growth and excretion of undigested food as white faeces. Additionally, while Vibrio infection can further exacerbate hepatopancreas dysfunction, its primary pathogenic mechanisms disrupt the gut through dysbiosis, mucosal damage, and inflammation.
Translucent Post-Larvae Disease (TPD) in shrimp is primarily associated with virulence factors produced by V. parahaemolyticus (VpTPD), notably Vibrio High Virulent Protein (VHVP)-1 and VHVP-2 (Liu et al., 2023). VpTPD disrupts the hepatopancreas and damages muscle tissue, leading to the loss of pigments and refractive proteins, which causes shrimp to exhibit a translucent appearance
The economic impact of vibriosis on the shrimp industry is substantial, with global losses reaching billions of pounds annually due to reduced growth rates, increased mortality, and the costs associated with disease management (Shinn et al., 2018; Dash et al., 2017). Shrimp are highly vulnerable to Vibrio infections, especially under high stocking densities, fluctuating water parameters, and inadequate biosecurity measures. The risk is further heightened by the emergence of antibiotic-resistant Vibrio strains, making treatment more challenging.
Effective control of vibriosis is crucial for sustainable shrimp farming. Implementing preventative measures such as optimal water quality management, balanced nutrition, and strict adherence to biosecurity protocols significantly reduces the risk of outbreaks (Chrisolite et al., 2025). Additionally, antibiotic-free alternatives, including phytogenic feed additives, are gaining recognition as sustainable solutions. As the shrimp industry continues to expand, understanding and mitigating the risks associated with Vibrio infections remain essential for ensuring productivity and profitability.
Purely Natural, Purely Effective: Vibrio Management for Optimal Shrimp Health.
Orego-Stim Forte has been extensively researched to demonstrate its efficacy in supporting shrimp health and performance during Vibrio challenges. All constituents of natural OEO and QS work together to provide a complex mode of action and support against vibriosis in shrimp.
Over 25 years of research has demonstrated that the Orego-Stim range naturally supports shrimp during Vibrio challenges.
Fine Particle Processing
Anpario’s innovative manufacturing process of Orego-Stim Forte encapsulates the oregano oil to enhance particle size, thermal stability, water solubility, protect the active ingredients and promote targeted absorption in the gastrointestinal tract.
- Related Trials
Trial Summary – In-Vitro Susceptibility Of Neoparamoeba Perurans To Orego-Stim Forte
Commercial Study Summary – Orego-Stim Supports Tilapia Health the Absence of Antibiotics
Trial Summary – Orego-Stim Proven Heat Stability in Pelleted Feeds
Trial Summary – Efficacy of Orego-Stim Forte Against Aquaculture Pathogens in Vitro
Trial Summary – Orego-Stim Forte Effect on Immune Response of Shrimp (Liptopenaeus Vannamei)
- Our Other Products
The Mastercube™ Range of pellet binders have been designed to improve milling efficiency whilst maximising the pellet quality of animal feed.
Mycotoxins are secondary fungal metabolites, produced by moulds, and are ubiquitous in the environment. Anpro® has been formulated from a unique, synergistic blend of mixed natural silicates for feed quality management of all livestock species.
Optomega® Algae is formulated on a unique mixed carrier system to provide a consistently high level of 100% natural DHA.
pHorce® is a highly concentrated liquid blend of pure formic and propionic acid, formulated on Anpario’s innovative mineral carrier system.
The Salgard® Range offers effective Acid Based Eubiotic (ABE) products, which consist of a unique blend of active ingredients, developed to help reduce the microbial load of drinking water sources and raw materials during feed processing.
Dr Lawrence Brown
(Senior Technical & Account Manager – Aqua)
Email: lawrence.brown@anpario.com
Telephone: +44 (0) 7540 689696
Gerred Fuchs
(Aqua Technical Sales Manager)
Email: gerred.fuchs@anpario.com
Telephone: +44 (0) 7720 461650
