SUMMARY
  • Escherichia coli is a wide spread bacteria prevalent in most livestock and has been linked to the transfer of antibacterial resistant coli to humans (Price et al., 2007).
  • pHorce improved broiler growth performance significantly by up to 12% when in high health and under E.coli challenge.
  • pHorce significantly improved the feed conversion ratio (FCR) by 8 points in challenged birds.

 

BACKGROUND
  • Deaths attributed to common infections resistant to antimicrobials will be the biggest killer in both humans and animals worldwide by 2050 (The Review on Antimicrobial Resistance, 2016).
  • pHorce is classified as a bacterial decontaminating agent (including, but not limited to Salmonella) to improve feed hygiene (Feed Additive Register 2017/940).

 

TRIAL DESIGN

A study was conducted in conjunction with São Paulo University, Brazil (2014). 750 Ross 308 broilers were randomly assigned to 2 groups, containing 2 treatments each. Group 1 was unchallenged while Group 2 was challenged orally with E. coli (K88 strain) at 7 days of age to induce a sub-clinical disease. Treatments were as follows Control; basal diets without pHorce, pHorce 1; Basal diets with 0.7kg/t pHorce in starter and 0.5kg/t pHorce in grower and finisher rations, pHorce 2; Basal diet with 1kg/t pHorce in starter 0.7kg/t in grower and 0.5kg/t in finisher. Measurements were taken at 35 days of age.

RESULTS
  • In both non-challenged and coli challenged birds, pHorce improved average daily gain (ADG) (0 – 35 days) significantly compared to the control at the higher inclusion.
  • Following coli challenge, pHorce improved overall FCR (0-35 days) and significantly so in the pHorce 2 group compared to the control, providing a benefit of 8 points.
  • A sub-clinical coli challenge was used to expose birds to a typical bacterial stressor similar to commercial poultry production. By helping to balance the microbiota, pHorce improved bird performance in both challenged and non-challenged birds.