- Orego-Stim did not interfere with the development of immunity to Eimeria following anticoccidial vaccination as shown by lesion scoring following coccidial challenge.
- Orego-Stim administered in water lessened the intestinal damage from coccidia leading to increased weight gain and lower lesion scores during challenge compared to Robenidine treatment.
- Eimeria as ubiquitous in the environment and there is no cross protection between Eimeria
- Traditionally coccidiosis control has been via the use of chemicals, ionophores and vaccines.
- The global cost of coccidiosis, including drug related treatment, is estimated to be $2-3 billion annually (Zhang et al., 2013).
- Orego-Stim is a high quality, plant based eubiotic, containing 100% natural oregano essential oil.
A study was conducted at Southern Poultry Research Inc, Georgia, USA. Birds (Cobb 500) were reared from 0‑42 days in floorpens on reused litter (see Table 1 for details). On Day 0, all birds were spray-vaccinated in the hatchery with a commercial coccidiosis vaccine (Coccivac-B, Merck Animal Health USA). On Day 21, 5 birds/pen were transferred to cages, challenged with Eimeria1 and 6 days later euthanized for lesion scoring. A Positive Control of cage-reared, naive, coccidia free birds were included to confirm an Eimeria challenge. Weight gain over the challenge period was determined.
Table 1. Treatment details
|Treatment||Floorpen phase||Challenge phase|
|No. birds/pen||No pens||No. birds/cage||No. cages|
|Positive control [POS]2||–||–||5||8|
|Robenidine (Robenz, 33 ppm) [ROB]||55||8||5||8|
|Orego-Stim (75ml/1000l) [OSL75]||55||8||5||8|
|Orego-Stim (150ml/1000l) [OSL150]||55||8||5||8|
|Orego-Stim (300ml/1000l) [OSL300]||55||8||5||8|
1 Per dose, approximately 100,000, 75,000, 50,000 oocysts of E. acervulina , E. maxima and E. teniella respectively; 2 Challenge phase only.
- ROB and OSL groups reduced gut lesions compared to POS. All OSL groups had lower lesion scores than ROB, with OSL 150 treatment having the lowest.
- Weight gain was significantly higher in all OSL groups over the challenge period compared to POS.
- Coccidial oocysts circulated in the litter at higher levels with OSL compared to ROB, allowing birds to build natural immunity to
- Orego-Stim Liquid administered in water supports bird performance during periods of intestinal stress, such as anticoccidial vaccination or coccidial challenge.