SUMMARY
  • Coccidiosis is an intestinal infection ubiquitous to poultry and is caused by several different species of Eimeria. Infection seriously impairs poultry growth and feed utilisation (Yun et al., 2000). Reducing the severity of coccidiosis can enhance performance and improve profitability.
  • In this study Orego-Stim® out-performed the positive control (challenged with no additives) and performed very close to the industry standard control, monensin sodium.
  • Orego-Stim® can help to alleviate the impact of coccidiosis following an Eimeria challenge and can be used as part of natural management programmes.

 

BACKGROUND
  • This work is part of the Anpario’s 4R approach (Review, Reduce and Replace antimicrobials Responsibly) which helps manage gut health and support healthier livestock through the use of natural products.
  • Orego-Stim® is a high quality, eubioitic composed of 100% natural oregano oil, containing the active compounds, carvacrol and thymol, which have been shown to reduce stress response in animals.

 

TRIAL DESIGN

An independent study was conducted at King Saud University, Saudi Arabia (Abudabos, 2019, Unpublished). The trial compares different natural coccidiostats and the industry standard control (monensin sodium) in the control of coccidiosis in challenged broilers. 392 Ross broilers (8 replicates of 7 birds each) were randomly allocated to 1 of 7 diets (Table 1) from 0 day old. At day 10, all birds except for the negative control, were individually challenged with Coccivac®, containing live oocysts (80 times overdose containing 8 broiler specific Eimeria spp.). Body weight gain (BWG), corrected feed conversion ratio (CFCR), corrected production efficiency factor (CPEF), intestinal lesion scores (using Johnson & Reid, 1970 method) and oocyte outputs were recorded for up to 30 days. Day 10-30 results are reported in this trial summary for brevity.

Table 1. Dietary treatments

Diet Treatment per Tonne of Feed Coccidiosis Challenge at Day 10
NC Negative Control: No additives No
PC Positive Control: No additives Yes
MS Monensin sodium: 0.5kg Yes
THB Encapsulated 3, 4, 5 – Trihydroxybenzoic Acid (THB):  0.075kg Yes
SP Saponin rich extracts (Protodioscine, Schidigera): 0.25kg Yes
OS Orego-Stim: 0.3kg Yes
PP Plant phytogenic additive: 0.3kg Yes
RESULTS

Broiler performance and production efficiency at day 30

Figure 1. Broiler performance at day 30 (20 days post challenge). abcdeDifferent superscripts differ significantly (p<0.05). Figure 2. Production efficiency at day 30 (20 days post challenge). abcdeDifferent superscripts differ significantly (p<0.05).

Intestinal leision scores and Eimeria oocyte output at day 30

Figure 3. Intestinal leision scores at day 30 (20 days post challenge). abDifferent superscripts differ significantly (p<0.05). Figure 4. Eimeria oocyte output at day 30 (20 days post challenge). abcDifferent superscripts differ significantly (p<0.05).
  • Orego-Stim significantly improved overall body weight gain (Fig. 1) compared to the positive control and saponin diet.
  • Orego-Stim also significantly reduced CFCR (Fig. 1) and improved CPEF (Fig. 2) compared to the positive control, trihydroxybenzoic acid diet and saponin diet.
  • Intestinal lesion scores (Fig. 3) were reduced by Orego-Stim compared to the positive control, with the lowest score recorded in the duodenum and jejunum (excluding negative control). The lesion scores in the caeca of Orego-Stim fed broilers were lower than broilers fed the positive control diet and saponin diet.
  • Oocyte output (Fig. 4) of broilers fed Orego-Stim was significantly reduced compared to the positive control, trihydroxybenzoic acid diet and saponin diet.
  • The lesion scores and oocyte output of Orego-Stim fed broilers were not significantly different to those fed the industry standard control, monensin sodium.